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Also known as active immunotherapy, this technique is to stimulate the body’s immune system to promote the production of antibodies. It is therefore no longer preventing the onset of a disease but to help the body of those already infected to fight against the disease by restoring immune defenses. It has been credited Auzias-Turenne to be caused by his method of syphilization, Shepherd took over with its vaccine against the rage. Contrary to popular belief; however, vaccination against rabies is not therapeutic. In fact, pre-exposure, it is a usual vaccination (injection of the antigen which will stimulate the production of specific defenses). In post-exposure, that is to say after being bitten by an animal may be rabid; it is a passive and active immunization.

Passive because there injection of immunoglobulin (antibody) specific against rabies and, at the same time, injection of rabies vaccine. Unlike AIDS or cancer, rabies vaccination is far more experimental. In August 1890 Robert Koch announced that he had discovered a substance that can cure TB: the tuberculin treatment should not keep its promises. Almroth Wright An article, published in 1902 entitled General on the treatment of localized bacterial infections by inoculation Vaccines containing bacteria, explained for the first time unambiguous theory of vaccine therapy.